PGA & HA: Kupititsa patsogolo kwa Synergistic, Nenani Bwino ku Kumamatira, Kunyowa ndi Kuphatikizika kwa Antioxidant

#Chiyambi

Sodium polyglutamate (PGA)ndi polima osungunuka m'madzi opangidwa ndikuyanika kwa tizilombo.Amagwiritsidwa ntchito kwambiri muchisamaliro chakhungumankhwala ndizodzoladzolachifukwa cha moisturizing zake zabwino kwambiri komanso multifunctional properties.Nkhaniyi ifotokoza za gwero, kapangidwe kake, mawonekedwe ndi kugwiritsa ntchitosodium polyglutamatemuzinthu zosamalira khungu mwatsatanetsatane.

#Source ndi Chemical Kapangidwe kake

Sodium polyglutamatechinapezeka koyamba mu natto, chakudya chachikhalidwe cha ku Japan.Silika wowoneka bwino kwambiri mu natto ndiPGA.Izi zimapangidwa ndi polymerized kuchokera ku glutamic acid yachilengedwe komanso yowonongeka ndipo imapangidwa ndi fermentation ya Bacillus subtilis.Bacillus subtilis ndi mtundu wapadziko lonse wodziwika bwino wa ma microbial additive (GRAS), wotengedwa mwachilengedwe komanso wotetezeka ku thupi la munthu.

Mapangidwe oyambira aPGAimapangidwa ndi 5000-10000 glutamic acid mamolekyulu polymerized kudzeraγ- amide zomangira.Molekyu ili ndi magulu ambiri a polar monga magulu a hydroxyl ndi carboxyl, omwe amatha kupanga zomangira za haidrojeni mkati ndi pakati pa mamolekyu, potero amamanga madzi ambiri ndikuwongolera kwambiri mphamvu yake yonyowa.

# Zowoneka ndi Zochita

1. **Kuchita bwino kwambiri moisturizing**: PGA imatha kuyamwa ndikutseka madzi ambiri, ndikupangitsa kuti khungu likhale labwino kwambiri.Mukagwiritsidwa ntchito ndisodium hyaluronate (HA), imatha kutalikitsa nthawi yonyowa ya HA, kuchepetsa kukhazikika kwake, ndikupangitsa khungu kukhala lachilengedwe komanso losalala.

2. **Antioxidant ntchito**: PGA ili ndi antioxidant ntchito, imatha kuwononga ma radicals aulere, ndikuteteza khungu kuti lisawonongeke ndi okosijeni.Kafukufuku wasonyeza kuti PGA yokhala ndi molekyulu yolemera ya 1.4 miliyoni Da imachita bwino pang'ono kuposa PGA yokhala ndi mamolekyulu olemera a 1 miliyoni Da mukusaka ma radicals aulere a DPPH.

3. **Wonjezerani zomwe zili mu chilengedwe cha moisturizing factor (NMF) pakhungu**: PGA imatha kulimbikitsa kubadwa kwa NMF pakhungu, kukulitsa luso lachilengedwe lonyowa pakhungu, ndikukwaniritsa chakudya chakuya.

4. **Whitening ndi anti-kukalamba**: PGA imatha kuwongolera pang'onopang'ono ntchito ya tyrosinase, kuchedwetsa mapangidwe a mawanga, ndipo nthawi yomweyo imathandizira kukhazikika kwa HA pakhungu, kukulitsa za HA, ndikukwaniritsa zotsatira za kuyera komanso kukana ukalamba.

#Kulemera kwa Mamolekyu ndi Kugwiritsa Ntchito

Malingana ndi kulemera kwa maselo, PGA ikhoza kugawidwa m'magulu atatu: kulemera kwakukulu kwa maselo, kulemera kwa maselo apakati ndi kulemera kochepa kwa maselo, iliyonse ili ndi makhalidwe ndi ntchito zosiyanasiyana:

- **PGA-HMW (kulemera kwa maselo,> 700kDa)**: kunyowa kwanthawi yayitali, kupanga filimu yonyezimira pakhungu, kuwongolera kwambiri mphamvu yamadzi.

- **PGA-LMW (zapakatikati molekyulu kulemera, 70-150kDa)**: kunyowetsa ndi kuyera, kumapangitsa kuti khungu likhale lowala komanso losalala.

- **PGA-Oligo (kuchepa kwa molekyulu, <10kDa)**: Chakudya chakuya, chofika mwachindunji ku basal layer, kulimbikitsa kubadwa kwa NMF ndi kuyamwa kwa michere.

# Malangizo Ogwiritsira Ntchito ndi Kugwiritsa Ntchito

PGA ndi oyenera moisturizing, anti-kukalamba ndi whitening mankhwala, ndi ndende analimbikitsa0.1% mpaka 1%.Ma anti-ionic emulsifiers ayenera kugwiritsidwa ntchito momwe angathere mu fomula kuti akwaniritse zotsatira za PGA.

#Mapeto

Monga biopolymer yachilengedwe, yotetezeka komanso yothandiza,sodium polyglutamate (PGA)ikuwonetsa kuthekera kwakukulu kogwiritsa ntchito pazosamalira khungu ndi zodzoladzola.Makhalidwe ake abwino kwambiri onyezimira, antioxidant ntchito komanso maubwino angapo ku thanzi lakhungu zimapangitsa kuti ikhale yofunika kwambiri pazinthu zamakono zosamalira khungu.Ndikukula kwa kafukufuku komanso kupita patsogolo kwaukadaulo wogwiritsa ntchito,PGAakuyembekezeka kuchita mbali yofunika kwambiri m'magawo ambiri ndikubweretsa zatsopano komanso chitukuko chaukadaulo wosamalira khungu.