HA PRO® ACETYLATED SODIUM HYALURONATE
Kufotokozera Kwachidule:
Sodium acetylated hyaluronate ndi Ankalumikiza mbali ya hydroxyl magulu a sodium hyaluronate mu acetyl magulu kudzera mankhwala anachita, kotero ali onse hydrophilicity ndi lipophilicity, amene akhoza kuimba pawiri moisturizing, antioxidant, odana ndi kutupa, kukonza keratin chotchinga, ndi kusintha khungu elasticity ndi zina. biologically yogwira ntchito.Zitha kupangitsa kuuma ndi kuuma kwa khungu kukhala bwino, kupangitsa khungu kukhala lofewa komanso zotanuka, ndipo zitha kugwiritsidwa ntchito kwambiri muzodzola zatsiku ndi tsiku.
Chiyambi cha Zamalonda
Thupi ndi mankhwala katundu: Maonekedwe ndi woyera kapena kuwala chikasu ufa, mosavuta sungunuka m'madzi.
Makhalidwe a mankhwala ali pansipa
1. Wonyowa kwambiri
2. Kutaya ma free radicals, anti-oxidant ndi anti-kukalamba
Kukonzekera koletsa kutupa
1. Wonyowa kwambiri
Saturated ammonium sulphate solution amagwiritsidwa ntchito kuti chinyezi chikhale cha 81%.Dziwani kusiyana kolemera pakati pa HA ndi AcHA ufa woyikidwa kwa 1h-8h, glycerin yolamulira bwino, imasonyeza kusungirako chinyezi;monga momwe tawonetsera pa Chithunzi 1, pomwe AcHA ndi nambala 2: Mayeso amasonyeza kuti mkati mwa 1h, AcHA ili ndipamwamba kwambiri kuposa glycerin ndi Kusungirako chinyezi cha HA wamba;mkati mwa 1-8h, kusungirako chinyezi kwa zitsanzo zonse kunawonongeka ndi nthawi, koma kusungirako chinyezi cha AcHA kunali kopambana kuposa kulamulira kwina.
HA1: otsika maselo kulemera sodium hyaluronate;HA2: acetylated sodium hyaluronate;
HA3: ochiritsira maselo kulemera sodium hyaluronate;
Chithunzi 1: Avereji ya kuchuluka kwa chinyezi pasampuli iliyonse panthawi iliyonse
2. Kutaya ma free radicals, anti-oxidant ndi anti-kukalamba
Mu njira ya ethanol, ma molekyulu a 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH) amatha kupanga ma nitrogen okhazikika okhala ndi ma free radicals.Imakhala ndi mayamwidwe amphamvu pa 517nm, ndipo mkangaziwisi waulere amatha kuphatikizira ndi elekitironi yake imodzi kuti athetse yankho.Mfundo imeneyi ntchito quantitatively kudziwa antioxidant mphamvu ya biologically yogwira zinthu.Kupyolera mu mayeso mmene m'badwo wa DPPH ufulu ankafuna kusintha zinthu mopitirira, zikusonyeza kuti poyerekeza ndi gulu ulamuliro, acetylated HA ali ndi mphamvu scavenge DPPH free ankafuna kusintha zinthu mopitirira, ndi kuposa ochiritsira maselo kulemera ufulu kwakukulu scavenging mlingo.
HA1: otsika maselo kulemera sodium hyaluronate;
AcHA: acetylated sodium hyaluronate
Chithunzi 2: Free radical scavenging rate of sodium acetylated hyaluronate
3.Kukonza anti-inflammatory
Mphamvu yotsutsa-kutupa idatsimikiziridwa ndi njira ya enzyme yolumikizidwa ndi immunosorbent.Kafukufuku wasonyeza kuti 1µg/mL lipopolysaccharide (LPS) imatha kulimbikitsa maselo a HaCaT kuti apange zinthu zoyambitsa kutupa, komanso kuthekera kwa zinthu zopangira kuletsa kuchuluka kwa zinthu zotupa kunayesedwa ndi ELISA.Monga momwe tawonetsera mu Chithunzi 3, poyerekeza ndi asidi wamba wa hyaluronic, mawu a 1L-1α mu gulu la acetylated hyaluronic acid adachepetsedwa kwambiri, ndipo mayesero amasonyeza kuti AcHA ili ndi mphamvu yaikulu yolepheretsa zinthu zotupa.
HA2: acetylated sodium hyaluronate;
HA3: ochiritsira maselo kulemera sodium hyaluronate:
Chithunzi 3: Kufotokozera kwa 1L-1α m'maselo mu zitsanzo zosiyanasiyana
Mafotokozedwe azinthu
Dzina la malonda | Acetylated sodium hyaluronate | |
Mafotokozedwe Akatundu | ufa woyera kapena wachikasu kapena granule | |
Zopindulitsa Zamalonda | Super moisturizing, AcHA ili ndi katundu wonyezimira kwambiri kuposa glycerin ndi HA wamba; Kusakaza ma free radicals, odana ndi makutidwe ndi okosijeni ndi odana ndi ukalamba, AcHA amatha scavenge DPPH free ankafuna kusintha zinthu mopitirira, ndipo kuposa ochiritsira maselo kulemera ufulu kwakukulu scavenging mlingo; Kuletsa kutupa ndi kukonza, AcHA ali ndi kuthekera kodziwikiratu kuletsa zinthu zotupa poyerekeza ndi asidi wamba wa hyaluronic; | |
Mafotokozedwe azinthu | Chizindikiritso | A. Infrared mayamwidwe spectrophotometry |
BA mtundu zimachitika ndi uroni zidulo | ||
C. Imapereka reaction (a) ya sodium | ||
Zomwe zili acetyl | 23.0-29.0% | |
pH | 5.0-7.0 | |
Kutaya pakuyanika | ≤10.0% | |
Zotsalira pa Ignition | 11.0% -16.0% | |
Kukhuthala kwamkati | 0.50-2.80dL/g | |
Chitsulo cholemera (monga Pb) | ≤20ppm | |
Arsenic | ≤2.0ppm | |
Nayitrogeni wambiri | 2.0-3.0% | |
Mabakiteriya amawerengera | ≤100CFU/g | |
Nkhungu & Yisiti | ≤30CFU/g | |
Staphylococcus aureus | Zoipa/g | |
Pseudomonas aeruginosa | Zoipa/g | |
Zosungirako | Sungani m'chipinda chopanda mpweya, chomwe chili ndi mthunzi. | |
Kulongedza | Malinga ndi zofuna za makasitomala | |
Alumali moyo | Zaka ziwiri (zopaka zosatsegulidwa) |
Malangizo ogwiritsira ntchito
Mlingo wovomerezeka: 0.01% -0.1%;
Kugwiritsa ntchito: kusungunuka mosavuta m'madzi, kungathe kuwonjezeredwa mwachindunji ku gawo la madzi;khungu limakhala lotsitsimula osati lomamatira
Ntchito zosiyanasiyana: zodzoladzola monga essence, chigoba kumaso, kirimu, mafuta odzola, etc.
Zosakaniza
Hyaluronic Acid & Tremella Fuciformis Polysaccharide
Collagen & Chondroitin Sulfate
Lumikizanani nafe
Adilesi
New Economic Development Zone ya High Speed Rail, Qufu, Jining, ShandongImelo
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